METFORMIN HYDROCHLORIDE
Metformin Hydrochloride (HCl) is the active pharmaceutical ingredient (API) used in the formulation of medications for the treatment of type 2 diabetes mellitus. It belongs to the biguanide class of antidiabetic drugs.
Chemical Name: N,N-Dimethylimidodicarbonimidic diamide hydrochloride
CAS Number: 1115-70-4
Molecular Formula: C4H11N5 · HCl
Molecular Weight: 165.62 g/mol
Appearance: White to off-white crystalline powder
Solubility: Freely soluble in water, slightly soluble in alcohol
Mechanism of Action:
- Reduces hepatic glucose production
- Increases insulin sensitivity in peripheral tissues
- Decreases intestinal glucose absorption
Key Features and Benefits:
- Effective in controlling blood glucose levels in patients with type 2 diabetes.
- Does not stimulate insulin secretion, thus minimizing the risk of hypoglycemia.
- May have additional benefits in weight management and cardiovascular health.
- Widely available and cost-effective API for generic drug manufacturers.
Applications:
- Primarily used in the manufacture of oral antidiabetic tablets and extended-release formulations.
- Combined with other antidiabetic drugs for enhanced glycemic control.
Storage and Handling:
- Store in a tightly closed container in a cool, dry place.
- Protect from light and moisture.
- Handle with appropriate safety measures.
Regulatory Status:
- Approved by major regulatory authorities for use in pharmaceutical products.
- Subject to specific quality standards and guidelines.
Important Note:
Metformin Hydrochloride API is intended for use by pharmaceutical manufacturers and should not be consumed directly. It must be formulated into finished pharmaceutical products and administered under the supervision of a healthcare professional.
Please consult with relevant pharmaceutical regulations and guidelines for specific details and requirements for the use of Metformin Hydrochloride API in drug manufacturing.