Niacinamide, also known as nicotinamide, is a form of vitamin B3 used in various cosmetic products and nutritional products.
Chemical Name: Pyridine-3-carboxamide
CAS Number: 98-92-0
Molecular Formula: C6H6N2O
Molecular Weight: 122.12 g/mol
Appearance: White crystalline powder
Solubility: Soluble in water, alcohol, and glycerol
Mechanism of Action:

• Niacinamide is a precursor to nicotinamide adenine dinucleotide (NAD+) and nicotinamide adenine dinucleotide phosphate (NADP+), coenzymes essential for various cellular processes, including energy metabolism, DNA repair, and cell signaling.
• It has anti-inflammatory, antioxidant, and skin-brightening properties.

Key Features and Benefits:

• Essential nutrient for maintaining overall health and preventing niacin deficiency.
• Used topically for various skin conditions, including acne, rosacea, and hyperpigmentation.
• May improve skin barrier function, reduce fine lines and wrinkles, and increase skin elasticity.
• Well-tolerated and suitable for most skin types.

Applications:

• Pharmaceutical formulations: Tablets, capsules, topical creams, and lotions
• Cosmetic products: Serums, moisturizers, toners, and masks
• Nutritional supplements: Multivitamins, B-complex vitamins

Storage and Handling:

• Store in a tightly closed container in a cool, dry place.
• Protect from light and moisture.

Regulatory Status:

• Approved by major regulatory authorities for use in pharmaceutical and cosmetic products.
• Subject to specific quality standards and guidelines.

Important Note:
Niacinamide is intended for use by pharmaceutical and cosmetic manufacturers and should not be consumed directly. It must be formulated into finished products and used as directed. While generally safe, high doses of niacinamide can cause mild side effects, such as nausea and headache.